JEE Main 2023 · 30 January · morning · Single correct · +4 / −1

To inhibit the growth of tumours, identify the compounds used from the following :
A. EDTA
B. Coordination Compounds of Pt
C. D - Penicillamine
D. Cis - Platin
Choose the correct answer from the option given below :

  1. (a) A and B Only
  2. (b) C and D Only
  3. (c) B and D Only
  4. (d) A and C Only
Answer and solution

Answer (c) B and D Only

Solution

Chemistry ma’am · 3 steps

Ask what each compound does in the body: two of them grab metals out, only platinum fights tumours.

  1. Chelating drugs. EDTA and D-penicillamine are chelating agents. They bind a toxic metal ion into a stable complex that the body can then excrete. That is metal removal, not tumour treatment.
  2. Platinum complexes. Cis-platin, cis-[Pt(NH₃)₂Cl₂], is a platinum complex that binds to the DNA of fast-dividing cells and stops them from copying it. This is why coordination compounds of Pt are used to stop tumours from growing.
    CompoundMedical useInhibits tumours?
    A. EDTAremoves lead in lead poisoningno
    B. Pt coordination compoundsanticancer drugsyes
    C. D-penicillamineremoves excess copper (Wilson's disease)no
    D. Cis-platinanticancer drugyes
  3. So. Only B and D inhibit tumour growth, so the answer is option (c).

The idea to keep. In coordination chemistry, chelating ligands like EDTA and D-penicillamine pull toxic metals out of the body, while platinum complexes like cis-platin are the anticancer drugs.

Answer from the NTA final answer key. Solution by PrepWiser.

Study Coordination Compounds

Asked about 250 times in JEE Main since 2020. This question is from 2023.