JEE Main 2022 · 29 June · morning · Single correct · +4 / −1

Sugar moiety in DNA and RNA molecules respectively are

  1. (a) β-D-2-deoxyribose, β-D-deoxyribose.
  2. (b) β-D-2-deoxyribose, β-D-ribose
  3. (c) β-D-ribose, β-D-2-deoxyribose.
  4. (d) β-D-deoxyribose, β-D-2-deoxyribose.
Answer and solution

Answer (b) β-D-2-deoxyribose, β-D-ribose

Solution

Chemistry ma’am · 3 steps

DNA is literally deoxyribonucleic acid: its sugar has lost the OH at C2. RNA keeps it.

  1. The sugar in RNA. RNA is ribonucleic acid. Its sugar is β-D-ribose, a five-carbon furanose sugar with an -OH group on every ring carbon from C1 to C3 and a -CH₂OH at C4.
  2. The sugar in DNA. DNA is deoxyribonucleic acid. Its sugar is the same ring, but the -OH at C2 is replaced by -H. That is why it is called β-D-2-deoxyribose.
    Nucleic acidGroup at C2Sugar
    DNA-Hβ-D-2-deoxyribose
    RNA-OHβ-D-ribose
  3. So. In the order DNA, then RNA, the sugars are β-D-2-deoxyribose and β-D-ribose, which is option (b).

The idea to keep. Both nucleic acids use a β-D pentose. The only difference is at C2: -OH in RNA's ribose, just -H in DNA's 2-deoxyribose. The 'deoxy' belongs only to DNA.

Answer from the NTA final answer key. Solution by PrepWiser.

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Asked about 150 times in JEE Main since 2020. This question is from 2022.