JEE Main 2021 · 27 July · morning · Single correct · +4 / −1

The compound 'A' is a complementary base of _______________ in DNA stands.

JEE Main PYQ figure
  1. (a) Uracil
  2. (b) Guanine
  3. (c) Adenine
  4. (d) Cytosine
Answer and solution

Answer (c) Adenine

Solution

Chemistry ma’am · 3 steps

Spot the methyl group on that pyrimidine ring: A is thymine, and thymine always pairs with adenine.

  1. Read the ring. A is a six-membered ring with two N atoms, so it is a pyrimidine base. It carries two C=O groups (at C2 and C4) and a CH₃ group at C5.
  2. Name the base. A pyrimidine with two C=O groups and no methyl is uracil. Adding the 5-methyl group makes it thymine (5-methyluracil), the base found in DNA.
    Base in DNATypeComplementary baseHydrogen bonds
    Thymine (A)pyrimidineAdenine (purine)2
    CytosinepyrimidineGuanine (purine)3
  3. So. In DNA, thymine pairs with adenine through two hydrogen bonds. Compound A is the complementary base of adenine, option (c).

The idea to keep. In DNA a purine always pairs with a pyrimidine: A with T (2 H-bonds), G with C (3 H-bonds). Thymine is just uracil with a CH₃ at C5.

Answer from the NTA final answer key. Solution by PrepWiser.

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Asked about 150 times in JEE Main since 2020. This question is from 2021.