JEE Main 2024 · 1 February · morning · Single correct · +4 / −1
If one strand of a DNA has the sequence ATGCTTCA, sequence of the bases in complementary strand is :
- (a) CATTAGCT
- (b) TACGAAGT
- (c) ATGCGACT
- (d) GTACTTAC
Answer and solution
Answer (b) TACGAAGT
Solution
Chemistry ma’am · 3 steps
Go base by base and swap each one for its partner: A pairs with T, and G pairs with C.
- Pairing rule. In DNA, adenine always pairs with thymine through 2 hydrogen bonds. Guanine always pairs with cytosine through 3 hydrogen bonds. So A ↔ T and G ↔ C.
- Swap each base. Read the given strand one base at a time: A → T, T → A, G → C, C → G, T → A, T → A, C → G, A → T.
A T G C T T C A ; T A C G A A G T
- So. The complementary strand reads TACGAAGT, which is option (b).
The idea to keep. A complementary strand is never a copy. Each base is replaced by its partner, A with T and G with C, and you keep the same order.
Answer from the NTA final answer key. Solution by PrepWiser.