JEE Main 2025 · 7 April · morning · Numerical answer · +4 / −1

Thyroxine, the hormone has given below structure
The percentage of iodine in thyroxine is __________ %. (nearest integer)
(Given molar mass in g mol⁻¹ C: 12, H: 1, O: 16, N: 14, I: 127 )

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Answer and solution

Answer 65

Solution

Chemistry ma’am · 2 steps

Count every atom from the structure, find the molar mass, then see what share the four iodines carry.

  1. Read the formula. Each benzene ring gives 6 C, and the side chain CH₂-CH(NH₂)-COOH adds 3 more. Each ring carries 2 I and 2 ring H. Oxygen comes from the OH, the ether bridge and the COOH group, so thyroxine is C₁₅H₁₁I₄NO₄.
    ElementAtomsMass (g mol⁻¹)
    C1515 × 12 = 180
    H4 + 1 + 2 + 1 + 2 + 1 = 1111 × 1 = 11
    I44 × 127 = 508
    N11 × 14 = 14
    O44 × 16 = 64
    Total35 atoms777

    % I = 508/777 × 100 = 65.38%

  2. So. The percentage of iodine in thyroxine is 65.38%, which rounds to 65.

The idea to keep. Mass percent of an element is (n × atomic mass)/(molar mass) × 100. From a structure, count hydrogens patiently: ring H, OH, NH2, CH2, CH and COOH all count.

Answer from the NTA final answer key. Solution by PrepWiser.

Study Mole Concept & Stoichiometry

Asked about 210 times in JEE Main since 2020. This question is from 2025.