JEE Main 2020 · 3 September · evening · Single correct · +4 / −1

Match the following drugs with their therapeutic actions :

(i) Ranitidine(a) Antidepressant
(ii) Nardil (Phenelzine)(b) Antibiotic
(iii)Chloramphenicol(c) Antihistamine
(iv)Dimetane (Brompheniramine)(d) Antacid
(e) Analgesic
  1. (a) (i)-(a); (ii)-(c); (iii)-(b); (iv)-(e)
  2. (b) (i)-(e); (ii)-(a); (iii)-(c); (iv)-(d)
  3. (c) (i)-(d); (ii)-(a); (iii)-(b); (iv)-(c)
  4. (d) (i)-(d); (ii)-(c); (iii)-(a); (iv)-(e)
Answer and solution

Answer (c) (i)-(d); (ii)-(a); (iii)-(b); (iv)-(c)

Solution

Chemistry ma’am · 3 steps

Think about what each drug actually does in the body, and the class name follows on its own.

  1. Match by action. Each drug is named after the job it does. Ask what problem it treats: acidity, low mood, bacterial infection or allergy.
    DrugWhat it doesClass
    (i) RanitidineBlocks H₂ receptors in the stomach wall, so less acid is released(d) Antacid
    (ii) Nardil (phenelzine)Inhibits the enzyme that breaks down noradrenaline, which lifts mood(a) Antidepressant
    (iii) ChloramphenicolBroad-spectrum drug that acts against bacteria(b) Antibiotic
    (iv) Dimetane (brompheniramine)Blocks histamine at its receptor, which relieves allergy symptoms(c) Antihistamine
  2. Rule out options. Ranitidine as an antacid leaves only (c) and (d). Nardil as an antidepressant then removes (d). Analgesic (e) is the extra option, and no drug matches it.
  3. So. The matching is (i)-(d), (ii)-(a), (iii)-(b), (iv)-(c), which is option (c).

The idea to keep. Ranitidine and brompheniramine both block histamine, but at different receptors. Blocking acid release in the stomach makes an antacid. Blocking the allergy response makes an antihistamine.

Answer from the NTA final answer key. Solution by PrepWiser.

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Asked about 60 times in JEE Main since 2020. This question is from 2020.