JEE Main 2020 · 5 September · morning · Single correct · +4 / −1
If a person is suffering from the deficiency of nor-adrenaline, what kind of drug can be suggested?
- (a) Anti-inflammatory
- (b) Antihistamine
- (c) Analgesic
- (d) Antidepressant
Answer and solution
Answer (d) Antidepressant
Solution
Chemistry ma’am · 3 steps
Low nor-adrenaline means low mood, so you need a drug that lifts mood: an antidepressant.
- What nor-adrenaline does. Nor-adrenaline is a neurotransmitter that helps control mood. When its level in the brain is low, signals that keep mood up get weaker, and the person becomes depressed.
- How the drug helps. Normally the enzyme that breaks down nor-adrenaline keeps its level in check. Antidepressants such as iproniazid and phenelzine block this enzyme, so nor-adrenaline lasts longer and the mood improves.
Drug class What it treats Fixes low nor-adrenaline? Anti-inflammatory Swelling and inflammation No Antihistamine Allergy, acidity (blocks histamine) No Analgesic Pain No Antidepressant Depression Yes, it raises nor-adrenaline activity - So. A person short of nor-adrenaline needs an antidepressant, option (d).
The idea to keep. Match the chemical messenger to the drug: low nor-adrenaline needs an antidepressant, while extra histamine needs an antihistamine.
Answer from the NTA final answer key. Solution by PrepWiser.