JEE Main 2021 · 16 March · morning · Single correct · +4 / −1

The functions of antihistamine are :

  1. (a) Antiallergic and Analgesic
  2. (b) Antacid and antialergic
  3. (c) Analgesic and antacid
  4. (d) Antiallergic and antidepressant
Answer and solution

Answer (b) Antacid and antialergic

Solution

Chemistry ma’am · 3 steps

Block histamine and you stop two things at once: allergy symptoms and acid release in the stomach.

  1. What histamine does. Histamine causes allergy symptoms such as sneezing, itching and a runny nose. It also tells the stomach wall to release hydrochloric acid. It acts on different receptors for each job.
    Histamine action blockedExample drugsUse
    Allergic responseBrompheniramine (Dimetapp), terfenadine (Seldane)Antiallergic
    Acid release in the stomachCimetidine (Tagamet), ranitidine (Zantac)Antacid
  2. Rule out the rest. Pain relief is the job of analgesics such as aspirin or morphine. Mood is the job of tranquilizers and antidepressants. Antihistamines do neither.
  3. So. Antihistamines work as both antacids and antiallergic drugs, which is option (b).

The idea to keep. Classify a drug by what it blocks. Block histamine and you stop both allergy symptoms and stomach acid release, so antihistamines are antiallergic and antacid.

Answer from the NTA final answer key. Solution by PrepWiser.

Study Chemistry in Everyday Life

Asked about 60 times in JEE Main since 2020. This question is from 2021.